研究主题:Diabetes, Mitochondria
详细题名日期
查看Group VIA Phospholipase A2 Mitigates Palmitate-Induced Beta Cell Mitochondrial Injury and Apoptosis.20140408
查看MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.20140408
查看The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity.20140408
查看BACH2, a candidate risk gene for type 1 diabetes, regulates apoptosis in pancreatic beta-cells via JNK1 modulation and crosstalk with the candidate gene PTPN2.20140408
查看Sex-dependent expression of caveolin 1 in response to sex steroid hormones is closely associated with development of obesity in rats.20140408
查看IL-1beta hampers glucose-stimulated insulin secretion in Cohen diabetic rat islets through mitochondrial cytochrome c oxidase inhibition by nitric oxide.20140408
查看Evaluation of mitochondrial divisions in mouse with type-2 diabetes and effect of glucose-oxidase on mouse islet cells RIN-m5F.20140408
查看Mitochondria in metabolic disease: Getting clues from proteomic studies.20140408
查看Intracellular and extracellular adenosine triphosphate in regulation of insulin secretion from pancreatic beta cells (beta).20140408
查看Antioxidant and regulatory role of mitochondrial uncoupling protein UCP2 in pancreatic beta-cells.20140317
查看Iron: the hard player in diabetes pathophysiology.20140317
查看Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12.20140317
查看Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic beta-cell function in diabetes.20140317
查看Albumin-bound fatty acids but not albumin itself alter redox balance in tubular epithelial cells and induce a peroxide-mediated redox-sensitive apoptosis.20140317
查看Chronic High Glucose and Pyruvate Levels Differentially Affect Mitochondrial Bioenergetics and Fuel-stimulated Insulin Secretion from Clonal INS-1 832/13 Cells.20140317
查看Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.20140317
查看JNK1 Protects against Glucolipotoxicity-Mediated Beta-Cell Apoptosis.20140217
查看Long term liver specific glucokinase gene defect induced diabetic cardiomyopathy by up regulating NADPH oxidase and down regulating insulin receptor and p-AMPK.20140217
查看Interleukin-1beta hampers glucose stimulated insulin secretion in Cohen diabetic rat islets through mitochondrial cytochrome c oxidase inhibition by nitric-oxide.20140217
查看The protective effects and genetic pathways of thorn grape seeds oil against high glucose-induced apoptosis in pancreatic beta-cells.20140217
查看Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin.20140217
查看The PARK2 gene is involved in the maintenance of pancreatic beta-cell functions related to insulin production and secretion.20140217
查看Treatment with glucokinase activator, YH-GKA, increases cell proliferation and decreases glucotoxic apoptosis in INS-1 cells.20140217
查看GYY4137, a novel hydrogen sulfide-releasing molecule, likely protects against high glucose-induced cytotoxicity by activation of the AMPK/mTOR signal pathway in H9c2 cells.20140102
查看Chronic high glucose and pyruvate levels differentially affect mitochondrial bioenergetics and fuel-stimulated insulin secretion from clonal INS-1 832/13 cells.20140102
查看Rap1 ameliorates renal tubular injury in diabetic nephropathy.20140102
查看At pharmacologically relevant concentrations intravenous iron preparations cause pancreatic beta cell death.20140102
查看[Progress in the role of oxidative stress in the pathogenesis of type 2 diabetes].20140102
查看Mitochondria in metabolic disease. Getting clues from proteomic studies.20140102
查看Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.20140102
查看Deconvoluting the role of reactive oxygen species and autophagy in human diseases.20140102
查看Amyloid beta-induced glycogen synthase kinase 3beta phosphorylated VDAC1 in Alzheimer's disease: Implications for synaptic dysfunction and neuronal damage.20140102
查看Evaluation of islets derived from human fetal pancreatic progenitor cells in diabetes treatment.20131203
查看Folate Deficiency Triggers an Oxidative-Nitrosative Stress-Mediated Apoptotic Cell Death and Impedes Insulin Biosynthesis in RINm5F Pancreatic Islet beta-Cells: Relevant to the Pathogenesis of Diabetes.20131203
查看Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.20131203
查看Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin.20131203
查看Rhein Protects Pancreatic beta-Cells From Dynamin-Related Protein-1-Mediated Mitochondrial Fission and Cell Apoptosis Under Hyperglycemia.20131203
查看C-Peptide Activates AMPKalpha and Prevents ROS-Mediated Mitochondrial Fission and Endothelial Apoptosis in Diabetes.20131203
查看Intracellular and extracellular ATP in regulation of insulin secretion from pancreatic beta cells.20131104
查看St. John's wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity.20131104
查看Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.20131104
查看The PARK2 gene is involved in the maintenance of pancreatic beta-cell functions related to insulin production and secretion.20131104
查看Long-Chain Acyl Coenzyme A Synthetase 1 Overexpression in Primary Cultured Schwann Cells Prevents Long Chain Fatty Acid-Induced Oxidative Stress and Mitochondrial Dysfunction.20131104
查看AMPK Regulates ER Morphology and Function in Stressed Pancreatic beta-Cells via Phosphorylation of DRP1.20131104
查看Chronic high glucose induced INS-1beta cell mitochondrial dysfunction: A comparative mitochondrial proteome with SILAC.20131104
查看Long-term liraglutide treatment is associated with increased insulin content and secretion in beta-cells, and a loss of alpha-cells in ZDF rats.20131104
查看Loss of Prohibitin Induces Mitochondrial Damages Altering beta-Cell Function and Survival and Is Responsible for Gradual Diabetes Development.20131104
查看Impaired autophagic function in rat islets with aging.20131104
查看Treatment with glucokinase activator, YH-GKA, increases cell proliferation and decreases glucotoxic apoptosis in INS-1 cells.20131002
查看Long-chain acyl coenzyme A synthetase 1 overexpression in primary cultured Schwann cells prevents long chain fatty acid-induced oxidative stress and mitochondrial dysfunction.20131002
查看Regulation of Mitochondrial Bioenergetic Function by Hydrogen Sulfide. Part II. Pathophysiological and Therapeutic Aspects.20131002
查看Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita+/Ins2-derived beta-cells.20131002
查看Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function.20131002
查看The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing.20131002
查看Impairment of pancreatic beta-cell function by chronic intermittent hypoxia.20131002
查看AMPK regulates ER morphology and function in stressed pancreatic beta-cells via phosphorylation of DRP1.20130902
查看Mangiferin from Salacia chinensis Prevents Oxidative Stress and Protects Pancreatic beta-Cells in Streptozotocin-Induced Diabetic Rats.20130902
查看Chronic high glucose-induced INS-1beta cell mitochondrial dysfunction: a comparative mitochondrial proteome with SILAC.20130902
查看Rhein protects pancreatic beta-cells from dynamin-related protein-1-mediated mitochondrial fission and cell apoptosis under hyperglycemia.20130902
查看Diabetes in Friedreich ataxia.20130902
查看High glucose induces mitochondrial p53 phosphorylation by p38 MAPK in pancreatic RINm5F cells.20130902
查看Long-term liraglutide treatment is associated with increased insulin content and secretion in beta-cells, and a loss of alpha-cells in ZDF rats.20130830
查看C-peptide activates AMPKalpha and prevents ROS-mediated mitochondrial fission and endothelial apoptosis in diabetes mellitus.20130830
查看Deconvoluting the role of reactive oxygen species and autophagy in human diseases.20130830
查看Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita+/Ins2-derived beta-cells.20130830
查看Fat cells directly sense temperature to activate thermogenesis.20130830
查看Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity.20130830
查看Cis-silencing of PIP5K1B evidenced in Friedreich's ataxia patient cells results in cytoskeleton anomalies.20130830
查看Galectin-3 deficiency protects pancreatic islet cells from cytokine-triggered apoptosis in vitro.20130830
查看Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function.20130702
查看The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing.20130702
查看Impaired Pancreatic Beta Cell Function by Chronic Intermittent Hypoxia.20130702
查看Cracking the O-GlcNAc code in metabolism.20130702
查看Effects of High Iron and Glucose Concentrations over the Relative Expression of Bcl2, Bax, and Mfn2 in MIN6 Cells.20130702
查看Bmal1 and beta-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced beta-cell failure in mice.20130702
查看Impaired Pancreatic Beta Cell Function by Chronic Intermittent Hypoxia.20130606
查看Activation of apocynin-sensitive NADPH oxidase (Nox2) activity in INS-1 832/13 cells under glucotoxic conditions.20130606
查看High glucose induces mitochondrial p53 phosphorylation by p38 MAPK in pancreatic RINm5F cells.20130606
查看Cracking the O-GlcNAc code in metabolism.20130606
查看O-GlcNAcomics - Revealing Roles of O-GlcNAcylation in Disease Mechanisms and Development of Potential Diagnostics.20130606
查看Dietary copper supplementation restores beta-cell function of Cohen diabetic rats: a link between mitochondrial function and glucose-stimulated insulin secretion.20130606
查看Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients.20130606
查看Antibody cross-reactivity and the viral aetiology of type 1 diabetes.20130606
查看Effects of High Iron and Glucose Concentrations over the Relative Expression of Bcl2, Bax, and Mfn2 in MIN6 Cells.20130430
查看Upregulation of p21 activates the intrinsic apoptotic pathway in beta cells.20130430
查看A prescribed Chinese herbal medicine improves glucose profile and ameliorates oxidative stress in Goto-Kakisaki rats fed with high fat diet.20130430
查看A C. elegans model to study human metabolic regulation.20130430
查看Cis-silencing of PIP5K1B evidenced in Friedreich's ataxia patient cells results in cytoskeleton anomalies.20130430
查看Bmal1 and beta-Cell Clock Are Required for Adaptation to Circadian Disruption, and Their Loss of Function Leads to Oxidative Stress-Induced beta-Cell Failure in Mice.20130430
查看Pancreatic stellate cells reduce insulin expression and induce apoptosis in pancreatic beta-cells.20130430
查看Identification of ATP synthase as a lipid peroxide protein adduct in pancreatic islets from humans with and without type 2 diabetes mellitus.20130430
查看14-3-3 proteins are essential signalling hubs for beta cell survival.20130430
查看Dietary copper supplementation restores beta-cell function of Cohen diabetic rats: a link between mitochondrial function and glucose-stimulated insulin secretion.20130330
查看Pancreatic stellate cells reduce insulin expression and induce apoptosis in pancreatic beta-cells.20130330
查看Identification of ATP synthase as a lipid peroxide protein adduct in pancreatic islets from humans with and without type 2 diabetes mellitus.20130330
查看Antibody cross-reactivity and the viral aetiology of type 1 diabetes.20130330
查看Manganese supplementation protects against diet-induced diabetes in wild type mice by enhancing insulin secretion.20130330
查看Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells.20130330
查看Metabolomic analysis of pancreatic beta cells following exposure to high glucose.20130330
查看Expression of beta human chorionic gonadotropin in the placenta of gestational diabetic mothers: an immunohistochemistry and ultrastructural study.20130228
查看Cadmium induces apoptosis in pancreatic beta-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation.20130228
查看Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients.20130228
查看Role of autophagy in the progression from obesity to diabetes and in the control of energy balance.20130228
查看D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-kappaB and PKC signaling.20130228
查看Low-intensity laser irradiation at 660 nm stimulates transcription of genes involved in the electron transport chain.20130228
查看The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats.20130228
查看Etiology of insulin resistance in youth with type 2 diabetes.20130228
查看A prescribed Chinese herbal medicine improves glucose profile and ameliorates oxidative stress in Goto-Kakisaki rats fed with high fat diet.20130131
查看Protective effect of oleanolic acid against beta cell dysfunction and mitochondrial apoptosis: crucial role of ERK-NRF2 signaling pathway.20130131
查看Genetic modulation of islet beta-cell iPLA(2)beta expression provides evidence for its impact on beta-cell apoptosis and autophagy.20130131
查看Cadmium induces apoptosis in pancreatic beta-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation.20130131
查看Manganese supplementation protects against diet-induced diabetes in wild type mice by enhancing insulin secretion.20130131
查看Role of autophagy in the progression from obesity to diabetes and in the control of energy balance.20130131
查看14-3-3 proteins are essential signalling hubs for beta cell survival.20130131
查看High glucose induced alteration of SIRTs in endothelial cells causes rapid aging in a p300 and FOXO regulated pathway.20130131
查看Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells.20130131
查看Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin.20130131
查看Quercetin and quercitrin protect against cytokineinduced injuries in RINm5F beta-cells via the mitochondrial pathway and NF-kappaB signaling.20130131
查看Hyperinsulinemia-induced vascular smooth muscle cell (VSMC) migration and proliferation is mediated by converging mechanisms of mitochondrial dysfunction and oxidative stress.20130131
查看Glitazones exert multiple effects on beta-cell stimulus-secretion coupling.20130131
查看The apoptosis inhibitor ARC alleviates the ER stress response to promote beta-cell survival.20130131
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