研究主题:Diabetes, Transcriptome, Proteome
详细题名日期
查看Nkx6.1 regulates islet beta-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors.20140408
查看Translational implications of the beta-cell epigenome in diabetes mellitus.20140408
查看Cellular reprogramming for pancreatic beta-cell regeneration: clinical potential of small molecule control.20140408
查看Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons.20140408
查看Could microRNAs contribute to the maintenance of beta cell identity?20140408
查看The Ability of Insulin to Inhibit Amyloid Formation by ProIAPP Processing Intermediates Is Significantly Reduced in the Presence of Sulfated Glycosaminoglycans.20140408
查看Characterization of Vector Based Delivery of Neurogenin-3 in Murine Diabetes.20140408
查看Integrative analysis reveals novel pathways mediating the interaction between adipose tissue and pancreatic islets in obesity in rats.20140408
查看MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.20140408
查看Curcumin ameliorates autoimmune diabetes. Evidences in accelerated murine models of type 1 diabetes.20140408
查看Thioredoxin-Interacting Protein Stimulates its Own Expression via a Positive Feedback Loop.20140408
查看Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through MIR-124A and FOXA2.20140408
查看The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity.20140408
查看Activity-guided isolation of NF-kappaB inhibitors and PPARgamma agonists from the root bark of Lycium chinense Miller.20140408
查看Berberine attenuates high glucose-induced proliferation and extracellular matrix accumulation in mesangial cells: Involvement of suppression of cell cycle progression and NF-kappaB/AP-1 pathways.20140408
查看IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets.20140408
查看Mitochondria in metabolic disease: Getting clues from proteomic studies.20140408
查看TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.20140408
查看A withanolide coagulin-L inhibits adipogenesis modulating Wnt/beta-catenin pathway and cell cycle in mitotic clonal expansion.20140408
查看Regenerating 1 and 3b Gene Expression in the Pancreas of Type 2 Diabetic Goto-Kakizaki (GK) Rats.20140317
查看The putative role of proteolytic pathways in the pathogenesis of Type 1 diabetes mellitus: The 'autophagy' hypothesis.20140317
查看Fractalkine signaling in regulation of insulin secretion: Mechanisms and potential therapeutic implications?20140317
查看Genome-wide Analysis of DNA Methylation Variations Caused by Chronic Glucolipotoxicity in Beta-Cells.20140317
查看Engineered Insulin Secretion from Neuroendocrine Cells Isolated From Human Thyroid.20140317
查看Anti-diabetic properties of a non-conventional radical scavenger, as compared to pioglitazone and exendin-4, in streptozotocin-nicotinamide diabetic mice.20140317
查看Iron: the hard player in diabetes pathophysiology.20140317
查看Activity-guided isolation of NF-kappaB inhibitors and PPARgamma agonists from the root bark of Lycium chinense Miller.20140317
查看Berberine attenuates high glucose-induced proliferation and extracellular matrix accumulation in mesangial cells: Involvement of suppression of cell cycle progression and NF-kappaB/AP-1 pathways.20140317
查看Pdx1 Maintains beta Cell Identity and Function by Repressing an alpha Cell Program.20140317
查看The temporal and hierarchical control of transcription factors-induced liver to pancreas transdifferentiation.20140317
查看Sequential introduction and dosage balance of defined transcription factors affect reprogramming efficiency from pancreatic duct cells into insulin-producing cells.20140317
查看A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell.20140317
查看Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice.20140317
查看Chronic High Glucose and Pyruvate Levels Differentially Affect Mitochondrial Bioenergetics and Fuel-stimulated Insulin Secretion from Clonal INS-1 832/13 Cells.20140317
查看Generation of insulin-producing cells from rat mesenchymal stem cells using an aminopyrrole derivative XW4.4.20140317
查看A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the "ARE2 Required for Viability" (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistance.20140317
查看Expression of Ins1 and Ins2 genes in mouse fetal liver.20140317
查看Nrf2 protects pancreatic beta-cells from oxidative and nitrosative stress in diabetic model mice.20140317
查看A new link between diabetes and cancer: enhanced WNT/beta-catenin signaling by high glucose.20140317
查看The temporal and hierarchical control of transcription factors-induced liver to pancreas transdifferentiation.20140217
查看Sequential introduction and dosage balance of defined transcription factors affect reprogramming efficiency from pancreatic duct cells into insulin-producing cells.20140217
查看Microarray analysis of rat pancreas reveals altered expression of alox15 and regenerating islet-derived genes in response to iron deficiency and overload.20140217
查看A Common Functional Regulatory Variant at a Type 2 Diabetes Locus Upregulates ARAP1 Expression in the Pancreatic Beta Cell.20140217
查看Short-term Type-1 diabetes differentially modulates 14-3-3 proteins in rat brain and liver.20140217
查看FFAs-ROS-ERK/P38 pathway plays a key role in adipocyte lipotoxicity on osteoblasts in co-culture.20140217
查看Differentiation of Human-Induced Pluripotent Stem Cells Into Insulin-Producing Clusters.20140217
查看Protective Action of Liraglutide in Beta Cells Under Lipotoxic Stress Via PI3K/Akt/FoxO1 Pathway.20140217
查看Suppressors of cytokine signaling (SOCS) and type 2 diabetes.20140217
查看Analysis of Transcription Factors Key for Mouse Pancreatic Development Establishes NKX2-2 and MNX1 Mutations as Causes of Neonatal Diabetes in Man.20140217
查看The protective effects and genetic pathways of thorn grape seeds oil against high glucose-induced apoptosis in pancreatic beta-cells.20140217
查看Effect of substrate rigidity in tissue culture on the function of insulin-secreting INS-1E cells.20140217
查看p85alpha deficiency protects beta-cells from endoplasmic reticulum stress-induced apoptosis.20140217
查看Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and beta-cell protection.20140217
查看Reprogramming of enteroendocrine K cells to pancreatic beta-cells through the combined expression of Nkx6.1 and Neurogenin3, and reaggregation in suspension culture.20140217
查看Generation of Functional Insulin-Producing Cells From Mouse Embryonic Stem Cells Through 804G Cell-Derived Extracellular Matrix and Protein Transduction of Transcription Factors.20140217
查看GATA factors promote ER integrity and beta-cell survival and contribute to type 1 diabetes risk.20140217
查看NF-kappaB and STAT1 control CXCL1 and CXCL2 gene transcription.20140217
查看Making surrogate beta-cells from mesenchymal stromal cells: perspectives and future endeavors.20140217
查看Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice.20140217
查看Down-regulation of pancreatic transcription factors and incretin receptors in type 2 diabetes.20140102
查看RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.20140102
查看A fusion protein derived from plants holds promising potential as a new oral therapy for type 2 diabetes.20140102
查看Bach2 Regulates Homeostasis of Foxp3+ Regulatory T Cells and Protects against Fatal Lung Disease in Mice.20140102
查看Reprogramming of enteroendocrine K cells to pancreatic beta-cells through the combined expression of Nkx6.1 and Neurogenin3, and reaggregation in suspension culture.20140102
查看Chronic high glucose and pyruvate levels differentially affect mitochondrial bioenergetics and fuel-stimulated insulin secretion from clonal INS-1 832/13 cells.20140102
查看[Progress in the role of oxidative stress in the pathogenesis of type 2 diabetes].20140102
查看Mitochondria in metabolic disease. Getting clues from proteomic studies.20140102
查看Glycogen Synthase Kinase-3beta Inhibition Augments Diabetic Endothelial Progenitor Cell Abundance and Functionality via Cathepsin B: a Novel Therapeutic Opportunity for Arterial Repair.20140102
查看Thymic Development of Autoreactive T Cells in NOD Mice Is Regulated in an Age-Dependent Manner.20140102
查看Deoxyhypusine synthase promotes differentiation and proliferation of T helper type 1 (Th1) cells in autoimmune diabetes.20140102
查看A rapidly evolving revolution in stem cell biology and medicine.20140102
查看Pathological endoplasmic reticulum stress mediated by the IRE1 pathway contributes to pre-insulitic beta cell apoptosis in a virus-induced rat model of type 1 diabetes.20140102
查看A new link between diabetes and cancer: enhanced WNT/beta-catenin signaling by high glucose.20140102
查看Expression profile of a clonal insulin-expressing epithelial cell in the thymus.20140102
查看VHL-mediated disruption of Sox9 activity compromises beta-cell identity and results in diabetes mellitus.20140102
查看29 GENERATION OF TRANSGENIC FIBROBLASTS EXPRESSING PANCREAS-SPECIFIC AND DOX-INDUCIBLE ICER Igamma IN A MINIATURE PIG MODEL OF HUMAN DIABETES MELLITUS.20140102
查看TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.20140102
查看IL-17A increases the expression of proinflammatory chemokines in human pancreatic islets.20140102
查看Rap1 ameliorates renal tubular injury in diabetic nephropathy.20140102
查看Generation of Functional Insulin-Producing Cells From Mouse Embryonic Stem Cells Through 804G Cell-Derived Extracellular Matrix and Protein Transduction of Transcription Factors.20131203
查看O-GlcNAc and the cardiovascular system.20131203
查看Generation of insulin-producing cells from rat mesenchymal stem cells using an aminopyrrole derivative XW4.4.20131203
查看GATA factors promote ER integrity, beta-cell survival, and contribute to type 1 diabetes risk.20131203
查看NF-kappaB and STAT1 control CXCL1 and CXCL2 Gene Transcription.20131203
查看Making surrogate beta-cells from mesenchymal stromal cells: Perspectives and future endeavors.20131203
查看A functional, genome-wide evaluation of liposensitive yeast identifies the ''ARE2 required for viability'' (ARV1) gene product as a major component of eukaryotic fatty acid resistance.20131203
查看Antioxidant effect of mogrosides against oxidative stress induced by palmitic acid in mouse insulinoma NIT-1 cells.20131203
查看Generation of Functional Insulin-Producing Cells from Neonatal Porcine Liver-Derived Cells by PDX1/VP16, BETA2/NeuroD and MafA.20131203
查看Expression of Ins1 and Ins2 genes in mouse fetal liver.20131203
查看A withanolide coagulin-L inhibits adipogenesis modulating Wnt/beta-catenin pathway and cell cycle in mitotic clonal expansion.20131203
查看Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice.20131203
查看A crosstalk between p21 and UPR-induced transcription factor C/EBP homologous protein (CHOP) linked to type 2 diabetes.20131203
查看Restoration of the Unfolded Protein Response in Pancreatic beta Cells Protects Mice Against Type 1 Diabetes.20131203
查看Enhancing the Function of CD34(+) Cells by Targeting Plasminogen Activator Inhibitor-1.20131203
查看Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1beta production and beta cell dysfunction.20131203
查看Thymic Development of Autoreactive T Cells in NOD Mice Is Regulated in an Age-Dependent Manner.20131203
查看Deoxyhypusine Synthase Promotes Differentiation and Proliferation of Th1 Cells in Autoimmune Diabetes.20131203
查看Nrf2 Protects Pancreatic beta-Cells from Oxidative and Nitrosative Stress in Diabetic Model Mice.20131203
查看The efficacy of SPA0355 in protecting beta cells in isolated pancreatic islets and in a murine experimental model of type 1 diabetes.20131203
查看Effect of Silymarin in Pdx-1 expression and the proliferation of pancreatic beta-cells in a pancreatectomy model.20131104
查看Pak3 promotes cell cycle exit and differentiation of beta-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice.20131104
查看Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion.20131104
查看Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells.20131104
查看Calcium/calmodulin-dependent serine protein kinase is involved in exendin-4-induced insulin secretion in INS-1 cells.20131104
查看Effect of Liraglutide on endoplasmic reticulum stress in diabetes.20131104
查看St. John's wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity.20131104
查看The transcription factor HNF1alpha induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs.20131104
查看Evaluation of Estrogenic Potential of Flavonoids Using a Recombinant Yeast Strain and MCF7/BUS Cell Proliferation Assay.20131104
查看Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6.20131104
查看Correction of diabetes mellitus by transplanting minimal mass of syngeneic islets into vascularized small intestinal segment.20131104
查看Impact of sterol regulatory element-binding factor-1c polymorphism on incidence of nonalcoholic fatty liver disease and on the severity of liver disease and of glucose and lipid dysmetabolism.20131104
查看The role of FOXO1 in beta-cell failure and type 2 diabetes mellitus.20131104
查看Caveolin-1/PTRF upregulation constitutes a mechanism for mediating p53-induced cellular senescence: implications for evidence-based therapy of delayed wound healing in diabetes.20131104
查看SOX1 suppresses cell growth and invasion in cervical cancer.20131104
查看Ex vivo expanded human regulatory T cells can prolong survival of a human islet allograft in a humanized mouse model.20131104
查看Resveratrol Prevents beta-Cell Dedifferentiation in Nonhuman Primates Given a High-Fat/High-Sugar Diet.20131104
查看Ebselen Treatment Prevents Islet Apoptosis, Maintains Intranuclear Pdx-1 and MafA Levels, and Preserves beta-Cell Mass and Function in ZDF Rats.20131104
查看Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats.20131104
查看Human omentum fat-derived mesenchymal stem cells transdifferentiates into pancreatic islet-like cluster.20131104
查看Treatment with glucokinase activator, YH-GKA, increases cell proliferation and decreases glucotoxic apoptosis in INS-1 cells.20131002
查看A new link between diabetes and cancer: enhanced Wnt/beta-catenin signalling by high glucose.20131002
查看Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6.20131002
查看Beta Cell 5'-Shifted isomiRs Are Candidate Regulatory Hubs in Type 2 Diabetes.20131002
查看The DPP-4 inhibitor MK0626 and exercise protect islet function in early pre-diabetic kkay mice.20131002
查看Correction of Diabetes Mellitus by Transplanting Minimal Mass of Syngeneic Islets Into Vascularized Small Intestinal Segment.20131002
查看Thioredoxin-interacting protein regulates insulin transcription through microRNA-204.20131002
查看Anthocyanins from Chinese Bayberry Extract Activate Transcription Factor Nrf2 in beta Cells and Negatively Regulate Oxidative Stress-Induced Autophagy.20131002
查看Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 beta-cell line.20131002
查看Influence of chronic hyperglycemia on the loss of the unfolded protein response in transplanted islets.20131002
查看Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions.20131002
查看Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome.20131002
查看Decoding cell death signals in liver inflammation.20131002
查看Impact of sterol regulatory element-binding factor-1c polymorphism on incidence of nonalcoholic fatty liver disease and on the severity of liver disease and of glucose and lipid dysmetabolism.20130902
查看Cellular responses of novel human pancreatic beta-cell line, 1.1B4 to hyperglycemia.20130902
查看Histone deacetylase inhibitor suppresses virus-induced proinflammatory responses and type 1 diabetes.20130902
查看Activation of the Transcriptional Function of the NF-kappaB Protein c-Rel by O-GlcNAc Glycosylation.20130902
查看Analysis of gene expression on ngn3 gene signaling pathway in endocrine pancreatic cancer.20130902
查看Thioredoxin-interacting protein regulates insulin transcription through microRNA-204.20130902
查看Connexin 36, a key element in pancreatic beta cell function.20130902
查看The role of FOXO1 in beta-cell failure and type 2 diabetes mellitus.20130902
查看Extrinsic Factors Promoting Insulin Producing Cell-Differentiation And Insulin Expression Enhancement-Hope For Diabetics.20130902
查看Radicicol Inhibits iNOS Expression in Cytokine-Stimulated Pancreatic Beta Cells.20130902
查看SOX1 suppresses cell growth and invasion in cervical cancer.20130902
查看Induction of beta-cell replication by a synthetic HNF4alpha antagonist.20130902
查看Ex Vivo Expanded Human Regulatory T Cells Can Prolong Survival of a Human Islet Allograft in a Humanized Mouse Model.20130902
查看In vivo activating transcription factor 3 silencing ameliorates the AMPK compensatory effects for ER stress-mediated beta-cell dysfunction during the progression of type-2 diabetes.20130902
查看Overexpression of E2F3 promotes proliferation of functional human beta cells without induction of apoptosis.20130902
查看A low-frequency GLIS3 variant associated with resistance to Japanese type 1 diabetes.20130902
查看The Role of SOX9 Transcription Factor in Pancreatic and Duodenal Development.20130902
查看Peroxisome Proliferator-activated Receptor gamma (PPARgamma) and Its Target Genes Are Downstream Effectors of FoxO1 Protein in Islet beta-Cells: MECHANISM OF beta-CELL COMPENSATION AND FAILURE.20130902
查看Glucose regulation of a cell cycle gene module is selectively lost in mouse pancreatic islets during ageing.20130902
查看The orphan nuclear receptor small heterodimer partner negatively regulates pancreatic beta cell survival and hyperglycemia in multiple low-dose streptozotocin-induced type 1 diabetic mice.20130902
查看Inhibition of the canonical Wnt pathway by high glucose can be reversed by parathyroid hormone-related protein in osteoblastic cells.20130902
查看Butyrate alleviates metabolic impairments and protects pancreatic beta cell function in pregnant mice with obesity.20130830
查看The negative cell cycle regulators, p27(Kip1), p18(Ink4c), and GSK-3, play critical role in maintaining quiescence of adult human pancreatic beta-cells and restrict their ability to proliferate.20130830
查看Insulin Receptor-Overexpressing beta-Cells Ameliorate Hyperglycemia in Diabetic Rats through Wnt Signaling Activation.20130830
查看Type 2 Diabetes Mellitus and Alzheimer's Disease: from physiopathology to treatment implications.20130830
查看Blockage of progesterone receptor effectively protects pancreatic islet beta cell viability.20130830
查看Bisphenol A: An endocrine and metabolic disruptor.20130830
查看Metabolic regulation of cellular plasticity in the pancreas.20130830
查看Synergistic expression of the CXCL10 gene in response to IL-1beta and IFN-gamma involves NF-kappaB, phosphorylation of STAT1 at Tyr701, and acetylation of histones H3 and H4.20130830
查看CRTC2 is required for beta-cell function and proliferation.20130830
查看Biliopancreatic diversion in nonobese patients with type 2 diabetes: impact and mechanisms.20130830
查看Preventing p38 MAPK-mediated MafA degradation ameliorates beta-cell dysfunction under oxidative stress.20130830
查看X-box binding protein 1 is essential for insulin regulation of pancreatic alpha-cell function.20130830
查看Preoperative fasting plasma C-peptide level may help to predict diabetes outcome after gastric bypass surgery.20130830
查看Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro.20130830
查看In vivo JNK activation in pancreatic beta-cells leads to glucose intolerance caused by insulin resistance in pancreas.20130830
查看The role of SOX9 transcription factor in pancreatic and duodenal development.20130702
查看Ebselen treatment prevents islet apoptosis, maintains intranuclear Pdx-1 and MafA levels, and preserves beta-cell mass and function in ZDF rats.20130702
查看PPARgamma and its Target Genes are Downstream Effectors of FoxO1 in Islet Beta-cells: Mechanism of Beta-cell Compensation and Failure.20130702
查看Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations.20130702
查看Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats.20130702
查看Coxsackievirus B4 can infect human pancreas ductal cells and persist in ductal-like cell cultures which results in inhibition of Pdx1 expression and disturbed formation of islet-like cell aggregates.20130702
查看A novel function of Onecut1 as a negative regulator of MafA.20130702
查看Pancreatic transdifferentiation in porcine liver following lentiviral delivery of human furin-cleavable insulin.20130702
查看A Short-activating RNA Oligonucleotide Targeting the Islet beta-cell Transcriptional Factor MafA in CD34(+) Cells.20130702
查看How to make a functional beta-cell.20130702
查看Imaging Beta cell regeneration and interactions with islet vasculature in transparent adult zebrafish.20130702
查看Cracking the O-GlcNAc code in metabolism.20130702
查看A Self-defeating Anabolic Program Leads to beta-Cell Apoptosis in Endoplasmic Reticulum Stress-induced Diabetes via Regulation of Amino Acid Flux.20130702
查看Extrinsic factors promoting in vitro differentiation of insulin-secreting cells from human adipose tissue-derived mesenchymal stem cells.20130702
查看Bmal1 and beta-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced beta-cell failure in mice.20130702
查看Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.20130702
查看Syntaxin-1a is a Direct Target of miR-29a in Insulin-producing beta-Cells.20130702
查看Human Umblical Cord Derived Mesenchymal Stem Cells Can Secret Insulin In Vitro and In Vivo.20130606
查看Cell-type, allelic and genetic signatures in the human pancreatic beta cell transcriptome.20130606
查看Nov/Ccn3, a Novel Transcriptional Target of FoxO1, Impairs Pancreatic beta-Cell Function.20130606
查看Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells.20130606
查看Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats.20130606
查看Glucose regulation of a cell cycle gene module is selectively lost in mouse pancreatic islets during ageing.20130606
查看Imaging Beta Cell Regeneration and Interactions with Islet Vasculature in Transparent Adult Zebrafish.20130606
查看The orphan nuclear receptor small heterodimer partner negatively regulates pancreatic beta cell survival and hyperglycemia in multiple low-dose streptozotocin-induced type 1 diabetic mice.20130606
查看CRTC2 is required for beta cell function and proliferation.20130606
查看Preventing p38 MAPK-mediated MafA degradation ameliorates beta cell dysfunction under oxidative stress.20130606
查看Cracking the O-GlcNAc code in metabolism.20130606
查看A Self-Defeating Anabolic Program Leads to beta cell apoptosis in ER Stress-Induced Diabetes via Regulation of Amino Acid Flux.20130606
查看O-GlcNAcomics - Revealing Roles of O-GlcNAcylation in Disease Mechanisms and Development of Potential Diagnostics.20130606
查看The role of the unfolded protein response in diabetes mellitus.20130606
查看Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes.20130606
查看Treatment of diabetes mellitus with microencapsulated fetal human liver (FH-B-TPN) engineered cells.20130606
查看Dicer1 is required to repress neuronal fate during endocrine cell maturation.20130606
查看Permanent Neonatal Diabetes in INSC94Y Transgenic Pigs.20130606
查看Failure of the Adaptive Unfolded Protein Response in Islets of Obese Mice Is Linked With Abnormalities in beta-Cell Gene Expression and Progression to Diabetes.20130606
查看Glucagon-like Peptide-1 triggers protective pathways in pancreatic Beta-cells exposed to glycated serum.20130430
查看TGF-beta Signaling Regulates Pancreatic beta-Cell Proliferation through Control of Cell Cycle Regulator p27 Expression.20130430
查看A CNS-Specific Hypomorphic Pdgfr-Beta Mutant Model of Diabetic Retinopathy.20130430
查看Extrinsic factors promoting in vitro differentiation of insulin-secreting cells from human adipose tissue-derived mesenchymal stem cells.20130430
查看Gene expression analysis of human islets in a subject at onset of type 1 diabetes.20130430
查看SLC29A3 mutation in a patient with syndromic diabetes with features of pigmented hypertrichotic dermatosis with insulin-dependent diabetes, H syndrome and Faisalabad histiocytosis.20130430
查看Bioluminescence imaging of beta cells and intrahepatic insulin gene activity under normal and pathological conditions.20130430
查看Caspase-14 suppresses GCM1 acetylation and inhibits placental cell differentiation.20130430
查看GLP-1(28-36) improves beta-cell mass and glucose disposal in streptozotocin induced diabetes mice and activates PKA-beta-catenin signaling in beta-cells in vitro.20130430
查看PPARgamma as a sensor of lipase activity and a target for the lipase inhibitor orlistat.20130430
查看Transcription factor gene MNX1 is a novel cause of permanent neonatal diabetes in a consanguineous family.20130430
查看Bmal1 and beta-Cell Clock Are Required for Adaptation to Circadian Disruption, and Their Loss of Function Leads to Oxidative Stress-Induced beta-Cell Failure in Mice.20130430
查看Collagen synthesis modulated in wounds treated by pulsed radiofrequency energy.20130430
查看Inhibition of NO-induced beta-cell death by novel NF-kappaB inhibitor (-)-DHMEQ via activation of Nrf2-ARE pathway.20130430
查看Functional plasticity of the human infant beta-cell exocytotic phenotype.20130430
查看Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions.20130430
查看Loss of T cell progenitor checkpoint control underlies leukemia initiation in Rag1-deficient nonobese diabetic mice.20130430
查看Dynamic expression of microRNAs during the differentiation of human embryonic stem cells into insulin-producing cells.20130430
查看The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis.20130430
查看Fetal PGC-1alpha overexpression programs adult pancreatic beta-cell dysfunction.20130430
查看Amyloid-beta induces hepatic insulin resistance in vivo via JAK2.20130430
查看Chronic activation of cannabinoid receptors in vitro does not compromise mouse islet function.20130430
查看Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic beta-cell survival and function via CREB.20130430
查看TGF-beta Signaling Regulates Pancreatic beta-Cell Proliferation through Control of Cell Cycle Regulator p27 Expression.20130330
查看Foxp3(+) regulatory T cells in mouse models of type 1 diabetes.20130330
查看Genetically reprogrammed, liver-derived insulin-producing cells are glucose-responsive, but susceptible to autoimmune destruction in settings of murine model of type 1 diabetes.20130330
查看PARP-1 and YY1 are important novel regulators of CXCL12 gene transcription in rat pancreatic beta cells.20130330
查看The role of the unfolded protein response in diabetes mellitus.20130330
查看Differential effects of interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic beta-cells.20130330
查看Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.20130330
查看Unexpected new roles for heparanase in Type 1 diabetes and immune gene regulation.20130330
查看X-box binding protein 1 is essential for insulin regulation of pancreatic alpha cell function.20130330
查看Raloxifene Upregulated Mesangial Cell MMP-2 Activity via ER-beta Through Transcriptional Regulation.20130330
查看Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes.20130330
查看Impaired tissue regeneration corresponds with altered expression of developmental genes that persists in the metabolic memory state of diabetic zebrafish.20130330
查看Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming.20130330
查看Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel.20130330
查看Blockade of receptor activator of nuclear factor-kappaB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus.20130330
查看Glucocorticoid-induced suppression of beta-cell proliferation is mediated by Mig6.20130330
查看Association study of STAT4 polymorphisms and type 1 diabetes in Northeastern Chinese Han population.20130330
查看Hyperplasia of pancreatic beta cells and improved glucose tolerance in mice deficient in the FXYD2 subunit of Na,K-ATPase.20130330
查看LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro.20130330
查看Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells.20130330
查看Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.20130330
查看Autonomous and self-sustained circadian oscillators displayed in human islet cells.20130330
查看PPAR-gamma -- a possible drug target for complicated pregnancies.20130330
查看Anti-inflammatory action of Tamarind seeds reduces hyperglycemic excursion by repressing pancreatic beta-cell damage and normalizing SREBP-1c concentration.20130330
查看The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis.20130330
查看Prevention of type 1 diabetes through infection with an intestinal nematode parasite requires IL-10 in the absence of a Th2-type response.20130330
查看Quercetin Preserves beta -Cell Mass and Function in Fructose-Induced Hyperinsulinemia through Modulating Pancreatic Akt/FoxO1 Activation.20130228
查看Inhibition of NO-induced beta-cell death by novel NF-kappaB inhibitor (-)-DHMEQ via activation of Nrf2-ARE pathway.20130228
查看Treatment of diabetes mellitus with microencapsulated fetal human liver (FH-B-TPN) engineered cells.20130228
查看Functional plasticity of the human infant beta-cell exocytotic phenotype.20130228
查看Impaired tissue regeneration corresponds with altered expression of developmental genes that persists in the metabolic memory state of diabetic zebrafish.20130228
查看Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development.20130228
查看Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro.20130228
查看Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming.20130228
查看Blockade of receptor activator of nuclear factor-kappaB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus.20130228
查看beta-cell dedifferentiation and type 2 diabetes.20130228
查看Glucocorticoid-induced suppression of beta-cell proliferation is mediated by Mig6.20130228
查看Dicer1 is required to repress neuronal fate during endocrine cell maturation.20130228
查看From pancreatic islet formation to beta-cell regeneration.20130228
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