Diabetes, Glucotoxicity, Oxidative Stress(13)
1 High Glucose Exposure Promotes Activation of Protein Phosphatase 2A in Rodent Islets and INS-1 832/13 beta-Cells by Increasing the Posttranslational Carboxylmethylation of Its Catalytic Subunit.
2 High fat fed obese Gpx1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage.
3 Endogenous hydrogen sulfide protects pancreatic beta-cells from a high-fat diet-induced glucotoxicity and prevents the development of type 2 diabetes.
4 A crosstalk between p21 and UPR-induced transcription factor C/EBP homologous protein (CHOP) linked to type 2 diabetes.
5 Caffeic acid, Naringenin and Quercetin enhance glucose stimulated insulin secretion and glucose sensitivity in INS-1E cells.
6 Glucose-stimulated oxidative stress in mononuclear cells is related to pancreatic beta-cell dysfunction in polycystic ovary syndrome.
7 Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.
8 Nrf2 Protects Pancreatic beta-Cells from Oxidative and Nitrosative Stress in Diabetic Model Mice.
9 Oral intralipid emulsion use: a novel therapeutic approach to pancreatic beta-cell injury caused by malathion toxicity in rats.
10 Antioxidant N-acetylcysteine protects pancreatic beta-cells against aldosterone-induced oxidative stress and apoptosis in female db/db mice and insulin-producing MIN6 cells.
11 gamma-Aminobutyric Acid Regulates Both the Survival and Replication of Human beta-Cells.
12 Glucotoxic conditions induce endoplasmic reticulum stress to cause caspase 3 mediated lamin B degradation in pancreatic beta-cells: protection by nifedipine.
13 Testosterone protects against glucotoxicity-induced apoptosis of pancreatic beta-cells (INS-1) and male mouse pancreatic islets.