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    在本期的信息速递中,我们为大家提供了16个专题,共计109条文献信息,影响因子8以上(IF≥8)的文献信息34条。与上期不同的是,本期的每条文献信息都增加了论文文摘,如果该论文是被Faculty of 1000 biology推荐的文章还附上了同行评议。此外,原热点扫描栏目改为科技管理栏目,报道国际上的相关科学政策和新闻消息。本期各专题的重要文章如下:


  Destruction or Potentiation of Different Prions Catalyzed by Similar Hsp104 Remodeling Activities{Yeast Ure2 and Prion [酵母Ure2蛋白和朊病毒]_1}

  Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins.{threee-dimensional structure of IGF[IGF的三维结构]_1}

  Platensimycin is a selective FabF inhibitor with potent antibiotic properties.{antimicrobial protein[抗微生物蛋白]_19}

  The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase.{EF-G(GTP)_3}

  Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation.{protein of SARS coronavirus[SARS病毒蛋白]_4}

  L-Type Ca2+ Channel Facilitation Mediated by Phosphorylation of the β Subunit by CaMKII{Calcium signaling in myocytes[肌细胞的钙离子信号通路]_9}

  The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication.{RecQ-helicase[RecQ家族DNA螺旋酶]_2}

  Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141. {Anti-SARS-Cov peptide[抗SARS病毒多肽]_1}

  The Radial Bias: A Different Slant on Visual Orientation Sensitivity in Human and Nonhuman Primates{Pattern motion and component motion sensitivity{Pattern motion and component motion sensitivity [模式运动和组成运动的敏感性]_3}

  Activation of P2Y1 nucleotide receptors induces inhibition of the M-type K+ current in rat hippocampal pyramidal neurons.{K+ current in hippocampal neurons[海马神经元的钾离子流]_1}

  Experience-dependent representation of visual categories in parietal cortex{Recognition of visual patterns [视觉模式的识别]_1}

  Cognitive Control Signals in Visual Cortex: Flashes Meet Spotlights{Cellular and molecular mechanism undering the precise anlysis and computation of neural signals[神经信号精确分析计算的细胞分子机制]_4}

  Inhibition of HIV-1 Gene Expression by a Fragment of hnRNP U{antiviral factor and HIV[抗病毒因子和艾滋病病毒]_10}

  Folding-based molecular simulations reveal mechanisms of the rotary motor F1-ATPase.{molecular motor and F0F(1) -ATPase[分子马达和F0F(1)-ATP酶]_2}

  Interleukin-4 supports interleukin-12-induced proliferation and interferon-gamma secretion in human activated lymphoblasts and T helper type 1 cells.{interferon gamma and tumor[γ-干扰素和肿瘤]_8}

  The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design {Avian influenza A (H5N1) viruses [禽流感A病毒H5N1]_2}


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