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题名:Embryonic stem-cell culture as a tool for developmental cell biology.
作者:Nishikawa S, Jakt LM, Era T,
来源:Nat Rev Mol Cell Biol. 2007 Jun;8(6):502-7[IF=29.85]
URL :http://dx.doi.org/10.1038/nrm2189
日期:070615
摘要:The cell biology of the early processes of mammalian embryogenesis, such as germ-layer formation, has been technically challenging to study owing to the size and accessibility of mammalian embryos. Embryonic stem cells, which can generate the three germ layers in vitro, are useful for studying embryogenesis at the cellular level. So, how can the study of embryonic stem cells and their differentiation provide a deeper understanding of the cell biology of early development?

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