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ISBN: 3540627537
题名: Proteome Research: New Frontiers in Functional Genomics
作者: Edit by. Wilkins, Marc R.; Williams, Keith L.; Appel, Ron D.; Hochstrasser,
出版社: Springer
页数: 243p
价格: EUR : 37.40
当前票数: 47
预版日期: 1997-1-1 0:00:00
文摘: 16Recent advances in 2D gel electrophoresis, protein microanalysis and bioinformatics have made possible the systematic analysis of proteins of a tissue or organism. This approach has aquired the name `Proteome` research, indicating that it can be considered as `the other side to the genome project`, and the results of proteome analysis have considerable significance for studies of genomes. Proteome research is also attracting considerable interest from pharmaceutical companies, and has extensive potential clinical applications. Proteome research is a systematic approach to characterising the protein complement of a tissue or organism, and can be considered a complementary approach to the genome project. 目次 `Keith L. Williams, Denis F. Hochstrasser, Introduction to the Proteome.- Ben R. Herbert, Jean-Charles Sanchez, Luca Bini, Two-Dimensional Electrophoresis: The State of the Art and Future Directions.- Marc R. Wilkins, Andrew A. Gooley, Protein Identification in Proteome Projects.- Andrew A. Gooley, Nicolle H. Packer, The Importance of Protein Co- and Post-translational Modifications in Proteome Projects.- Amos Bairoch, Proteome Databases.- Ron D. Appel, Interfacing and Integrating Databases.- Manuel C. Peitsch, Nicolas Guex, Large-Scale Comparative Protein Modelling.- Denis F. Hochstrasser, Clinical and Biomedical Applications of Proteomics.- Keith L.Williams, Vitaliano Pallini, Biological Applications of Proteomics.- Denis F. Hochstrasser, Keith L.Williams, Conclusions.`
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